Game Starts, and immediately says not responding

Whenever I start terraria, it opens, but cannot be played, not even getting to the title screen. It immediately goes into "Not responding" and does nothing. It will go on like this for as long as I leave it. After closing it, the error log file showed this:

Error Logging Enabled.
================
7/29/2018 9:26:08 PM: First-Chance Exception
Culture: en-US
Exception: System.IO.IOException: The handle is invalid.
at System.IO.__Error.WinIOError(Int32 errorCode, String maybeFullPath)...

Game Starts, and immediately says not responding